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Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease (eBook)

Artikelnummer: 978-94-007-5416-4
Einband: PDF
Verfügbarkeit: Download, sofort verfügbar (Link per E-Mail)
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This volume of the Subcellular Biochemistry series is devoted to the aggregation and fibrillogenesis of the amyloid-forming peptides and proteins, including emphasis on oligomer formation as well as fibril formation. The diverse topics included here are presented within 22 chapters, covering many of the relevant topics from both a basic science and clinical perspective. The authorship of these chapters is thoroughly international, with authoritative contributions from active researchers. Fundamental structural and cellular studies using many different technical approaches are presented, leading through to clinical and therapeutic aspects of the amyloid diseases, considered from both pharmaceutical and natural product view points. It is hoped that this book will be of use to both biomedical scientists and clinicians wishing to keep abreast of this rapidly advancing field, of direct importance to the understanding of cerebral neurodegenerative disease and systemic amyloid disease.


This volume of the Subcellular Biochemistry series is devoted to the aggregation and fibrillogenesis of the amyloid-forming peptides and proteins, including emphasis on oligomer formation as well as fibril formation. The diverse topics included here are presented within 22 chapters, covering many of the relevant topics from both a basic science and clinical perspective. The authorship of these chapters is thoroughly international, with authoritative contributions from active researchers. Fundamental structural and cellular studies using many different technical approaches are presented, leading through to clinical and therapeutic aspects of the amyloid diseases, considered from both pharmaceutical and natural product view points. It is hoped that this book will be of use to both biomedical scientists and clinicians wishing to keep abreast of this rapidly advancing field, of direct importance to the understanding of cerebral neurodegenerative disease and systemic amyloid disease.


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VerlagSpringer Netherlands
EinbandPDF
Erscheinungsjahr2012
Seitenangabe650 S.
AusgabekennzeichenEnglisch
AbbildungenXVIII, 650 p.
Masse11'492 KB
PlattformPDF
ReiheSubcellular Biochemistry; Biomedical and Life Sciences; Biomedical and Life Sciences
AutorHarris, J. Robin (Hrsg.)

Alle Bände der Reihe "Subcellular Biochemistry; Biomedical and Life Sciences; Biomedical and Life Sciences (R0)"

Über den Autor J. Robin (Hrsg.) Harris

J. Robin Harris is a retired structural biologist and electron microscopist. He is an Honorary Professor of the University of Mainz, Germany, where he worked with the group of Professor Juergen Markl, in the Institute of Zoology. Since taking retirement, Robin continued part-time research for several years at the Newcastle University, UK, and acted as an Editor of the Elsevier journal micron and as Series Editor of the long-standing Springer book series Subcellular Biochemistry. Jon Marles-Wright obtained his Ph.D. in structural biology from the University of Oxford, where he focused on understanding how human immune receptors interact with their targets. For his post-doctoral training, he moved to the University of Newcastle, where his research focus moved to bacterial cell biology. In 2012 Jon was appointed to a two-year career development fellowship at the University of Newcastle where he developed his interest in the structural basis of metabolic compartmentalization within bacteria. This was followed by nearly four years at The University of Edinburgh as a Chancellor's Fellow in the Institute of Structural and Molecular Biology and Centre for Systems and Synthetic Biology. Jon is currently a Senior Lecturer in Microbial Biotechnology in the School of Biology at Newcastle University.

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