Clinical Trial Biostatistics and Biopharmaceutical Applications

With contributions from leaders in the biostatistical community, this book presents novel biostatistical methodologies in clinical trials as well as up-to-date biostatistical applications from the pharmaceutical industry. It covers emerging issues in clinical trial design and analysis, adaptive clinical trial designs, oncology clinical trials, m"This book of timely, self-contained chapters covers a wide range of current methods and unresolved challenges in clinical trial statistical methods and will prove to be an essential guide for biostatisticians who work in this field."-Dirk F. Moore, Journal of Biopharmaceutical Statistics". . . the contributed chapters in this collection are clearly written, easily digestible, and well-referenced. The book is a useful resource for the clinical trialist interested in obtaining a quick overview of standard practices and current methodological development for a specific biostatistical application, or a worthwhile read for the researcher seeking to familiarize him or herself with a diversity of emerging topics in clinical trials.-Megan T. Smith, University of California, Irvine